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	Provedor de dados BJMBR (2) Autor Boer,P.A. (2) Gontijo,J.A.R. (2) Mesquita,F.F. (1) Michelotto,J.B. (1) Oliveira,P.C. (1) Zapparoli,A. (1) Mais... Palavra-chave Angiotensin receptors (1) Blood pressure (1) Central nervous system (1) Glucocorticoids (1) Insulin (1) Intracerebroventricular (1) Lithium clearance (1) Maternal undernutrition (1) Natriuresis (1) Nephrogenesis (1) Nitric oxide inhibition (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2010 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Consequences of cerebroventricular insulin injection on renal sodium handling in rats: effect of inhibition of central nitric oxide synthase BJMBR Oliveira,P.C.; Michelotto,J.B.; Zapparoli,A.; Boer,P.A.; Gontijo,J.A.R.. In the present study, we investigated the effects of acute intracerebroventricular (icv) insulin administration on central mechanisms regulating urinary sodium excretion in simultaneously centrally NG-nitro-L-arginine methylester (L-NAME)-injected unanesthetized rats. Male Wistar-Hannover rats were randomly assigned to one of five groups: a) icv 0.15 M NaCl-injected rats (control, N = 10), b) icv dose-response (1.26, 12.6 and 126 ng/3 µL) insulin-injected rats (N = 10), c) rats icv injected with 60 µg L-NAME in combination with NaCl (N = 10) or d) with insulin (N = 10), and e) subcutaneously insulin-injected rats (N = 5). Centrally administered insulin produced an increase in urinary output of sodium (NaCl: 855.6 ± 85.1 Δ%/min; 126 ng insulin: 2055 ± 310.6... Tipo: Info:eu-repo/semantics/article Palavras-chave: Central nervous system; Intracerebroventricular; Nitric oxide inhibition; Insulin; Natriuresis; Lithium clearance. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200013 Maternal undernutrition and the offspring kidney: from fetal to adult life BJMBR Mesquita,F.F.; Gontijo,J.A.R.; Boer,P.A.. Maternal dietary protein restriction during pregnancy is associated with low fetal birth weight and leads to renal morphological and physiological changes. Different mechanisms can contribute to this phenotype: exposure to fetal glucocorticoid, alterations in the components of the renin-angiotensin system, apoptosis, and DNA methylation. A low-protein diet during gestation decreases the activity of placental 11ß-hydroxysteroid dehydrogenase, exposing the fetus to glucocorticoids and resetting the hypothalamic-pituitary-adrenal axis in the offspring. The abnormal function/expression of type 1 (AT1R) or type 2 (AT2R) AngII receptors during any period of life may be the consequence or cause of renal adaptation. AT1R is up-regulated, compared with control, on... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nephrogenesis; Blood pressure; Angiotensin receptors; Glucocorticoids; Maternal undernutrition. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100001 Registros recuperados: 2 Primeira ... 1 ... Última

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